I have always made sure I delete all old saved "homes" because there is nothing like typing in an "old" /sethome from the previous map and finding myself 3000ft in the air or under the ocean :)
If you are using backpacks and do not delete the data file it will retain all the contents of the backpack into the new map whether or no its a completely different seed.
If you are on a hosted server the new updates will wipe all blueprints automatically on a BP wipe and all wipes will remove all inventory items and player structures, Some plugins like inventory guardian can save inventories and there are blueprint manager plugins but generally they will be wiped,
There are plugins like Zlevels remastered that enable you to gain greater resource gathering levels, these will not reset to default, Nor will PlayerRankings ranks go back to default, I am not sure of how "Player Ranks" or "gather manager" handle wipes, Your setting for Botspawn, Monument Radiation, Radtown Animals, Helicontrol, Compound Options, FancyDrop and Custom animal spawns will not be affected ,
They are a small example of unaffected plugins during wipes, though you will have to make sure that for any plugins you use that you have selected the "watch" function as wipe time is sometimes "update" time because of changes made to the game.