There are oxide compiler mods that I've seen for Python and Javascript, aside from the normal CSharp comipler. Are these required to run plugins here? I dont think that I've seen any plugins that run Python, but I know that a majority of the plugins use JSON's for configs. 

The files im talking about are oxide.core.javascript.dll and oxide.core.python.dll and the regular CSharp file is oxide.CSharp.dll. If these dont need to be installed, than im not going to bother with them.

There are no Python or JavaScript plugins publicly anymore, we dropped support for those years ago with no plans of updating or supporting again. If you or your host are installing those files, then you can remove them, as they are not updated and not used.

Perfect, thats exactly what I wanted to know. I appreciate the response Wulf!